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Life Sci 1997, 60: 1933-1942

The compound progressed through Phase 2 trials under multiple sponsors for postoperative ileus and related gastric-motility indications, with one randomized controlled trial published in 2014, but did not advance to a marketed therapeutic in any major jurisdiction

More serious side effects are rare but can include pancreatitis and thyroid tumors

For instance, forms of several B vitamins, including thiamin, riboflavin, niacin, and pantothenic acid, as well as the compound lipoic acid, are utilized in reactions that completely metabolize glucose to carbon dioxide and water (3)

Of course, there is stigma